"Discovery is seeing what everybody else has seen, and thinking what nobody else has thought."
-- Albert Szent-Györgyi (1893 - 1986)
I don't know how I missed it, but the Pythagorean trigonometric identity is a special case of the generalized half-angle formulas.
The following is a generalization of the half-angle formulas presented at Nabla - Applications of Trigonometry for a triangle.
Generalization. Let $a$, $b$, $c$, $d$ be the sides of a general convex quadrilateral, $s$ is the semiperimeter, and $\alpha$ and $\gamma$ are opposite angles, then
$$ad\sin^2{\frac{\alpha}{2}}+bc\cos^2{\frac{\gamma}{2}}=(s-a)(s-d).\tag{1}$$
For a proof of $(1)$ see pp. 8 in MATINF.
The Pythagorean identity as a special case
In $(1)$, consider the case when $a=c$, $b=d$ and $\alpha=\gamma$ so that the quadrilateral is a parallelogram . Then
$$ab\sin^2{\frac{\alpha}{2}}+ab\cos^2{\frac{\alpha}{2}}=\frac{-a+b+c+d}{2}\cdot{\frac{a+b+c-d}{2}}=ab.$$Dividing both sides by $ab$ you get
$$\sin^2{\frac{\alpha}{2}}+\cos^2{\frac{\alpha}{2}}=1.$$
Or by making $\frac{\alpha}{2}=\theta$,
$$\sin^2{\theta}+\cos^2{\theta}=1,$$
which is the Pythagorean trigonometric identity.
For more implications of $(1)$ I invite you to see The theoretical importance of the half-angle formulas.